Flow Patterns and Particle Residence Times in the Oral Cavity during Inhaled Drug Delivery

Flow Patterns and Particle Residence Times in the Oral Cavity during Inhaled Drug Delivery

Pulmonary drug delivery aims to deliver particles deep into the lungs, bypassing the mouth–throat airway geometry. However, micron particles under high flow rates are susceptible to inertial impaction on anatomical sites that serve as a defense system to filter and prevent foreign particles from ent...

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Bibliographic Details
Main Authors: Brenda Vara Almirall, Kiao Inthavong, Kimberley Bradshaw, Narinder Singh, Aaron Johnson, Pippa Storey, Hana Salati
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceuticals
Subjects:
CFD modeling
oral cavity
respiration
targeted drug delivery
SBES
Online Access:https://www.mdpi.com/1424-8247/15/10/1259

Internet

https://www.mdpi.com/1424-8247/15/10/1259

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