Fresh and Cryopreserved Human Umbilical-Cord-Derived Mesenchymal Stromal Cells Attenuate Injury and Enhance Resolution and Repair following Ventilation-Induced Lung Injury

Fresh and Cryopreserved Human Umbilical-Cord-Derived Mesenchymal Stromal Cells Attenuate Injury and Enhance Resolution and Repair following Ventilation-Induced Lung Injury

Background: Ventilator-induced lung injury (VILI) frequently worsens acute respiratory distress syndrome (ARDS) severity. Human mesenchymal stem/stromal cells (MSCs) offer considerable therapeutic promise, but the key impediments of clinical translation stem from limitations due to cell source and a...

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Bibliographic Details
Main Authors: Shahd Horie, Hector Gonzalez, Jack Brady, James Devaney, Michael Scully, Daniel O’Toole, John G. Laffey
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
acute respiratory distress syndrome
ventilation-induced lung injury
injury
mesenchymal stem/stromal cells
cryopreservation
tissue source
Online Access:https://www.mdpi.com/1422-0067/22/23/12842

Internet

https://www.mdpi.com/1422-0067/22/23/12842

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