Bivariate genome-wide association analyses identified genes with pleiotropic effects for femoral neck bone geometry and age at menarche.

Bivariate genome-wide association analyses identified genes with pleiotropic effects for femoral neck bone geometry and age at menarche.

Femoral neck geometric parameters (FNGPs), which include cortical thickness (CT), periosteal diameter (W), buckling ratio (BR), cross-sectional area (CSA), and section modulus (Z), contribute to bone strength and may predict hip fracture risk. Age at menarche (AAM) is an important risk factor for os...

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Bibliographic Details
Main Authors: Shu Ran, Yu-Fang Pei, Yong-Jun Liu, Lei Zhang, Ying-Ying Han, Rong Hai, Qing Tian, Yong Lin, Tie-Lin Yang, Yan-Fang Guo, Hui Shen, Inderpal S Thethi, Xue-Zhen Zhu, Hong-Wen Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3617200?pdf=render

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http://europepmc.org/articles/PMC3617200?pdf=render

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