Cannabidiol Decreases Intestinal Inflammation in the Ovariectomized Murine Model of Postmenopause

Cannabidiol Decreases Intestinal Inflammation in the Ovariectomized Murine Model of Postmenopause

Cannabidiol (CBD) (25 mg/kg peroral) treatment was shown to improve metabolic outcomes in ovariectomized (OVX) mice deficient in 17β-estradiol (E2). Herein, CBD effects on intestinal and hepatic bile acids (BAs) and inflammation were investigated. Following RNA sequencing of colon tissues from vehic...

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Bibliographic Details
Main Authors: Karen Mae A. Bacalia, Kevin M. Tveter, Hayley Palmer, Jeffrey Douyere, Savannah Martinez, Ke Sui, Diana E. Roopchand
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
cannabidiol
inflammation
bile acids
transcriptomics
estrogen deficiency
ovariectomized mice
Online Access:https://www.mdpi.com/2227-9059/11/1/74

Internet

https://www.mdpi.com/2227-9059/11/1/74

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