Targeting the apoptosis pathway to treat tumours of the paediatric nervous system

Abstract New, more effective therapeutics are required for the treatment of paediatric cancers. Current treatment protocols of cytotoxic treatments including chemotherapy trigger cancer-cell death by engaging the apoptosis pathway, and chemotherapy efficacy is frequently impeded by apoptosis dysregu...

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Bibliographic Details
Main Authors: Marie-Claire Fitzgerald, Philip J. O’Halloran, Niamh M. C. Connolly, Brona M. Murphy
Format: Article
Language:English
Published: Nature Publishing Group 2022-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04900-y