Targeting the apoptosis pathway to treat tumours of the paediatric nervous system
Abstract New, more effective therapeutics are required for the treatment of paediatric cancers. Current treatment protocols of cytotoxic treatments including chemotherapy trigger cancer-cell death by engaging the apoptosis pathway, and chemotherapy efficacy is frequently impeded by apoptosis dysregu...
Main Authors: | Marie-Claire Fitzgerald, Philip J. O’Halloran, Niamh M. C. Connolly, Brona M. Murphy |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-05-01
|
Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-04900-y |
Similar Items
-
The identification of BCL-XL and MCL-1 as key anti-apoptotic proteins in medulloblastoma that mediate distinct roles in chemotherapy resistance
by: Marie-Claire Fitzgerald, et al.
Published: (2023-10-01) -
Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours
by: Arash Nabbi, et al.
Published: (2023-09-01) -
Dexamethasone use in paediatric central nervous system tumours: a review of current literature
by: S. Morrison, et al.
Published: (2021-01-01) -
Frequency and characterization of cognitive impairments in patients diagnosed with paediatric central nervous system tumours: a systematic review
by: Francesco Sciancalepore, et al.
Published: (2023-05-01) -
Zebrafish Models of Paediatric Brain Tumours
by: Faiza Basheer, et al.
Published: (2022-08-01)