Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer

Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer

Abstract Background Emerging evidence suggests that PIWI-interacting RNAs (piRNAs) may be important epigenetic regulators of gene expression in human cancers; however, their functional and clinical significance in colorectal cancer (CRC) remains unknown. Methods We performed piRNA expression profili...

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Bibliographic Details
Main Authors: Wenhao Weng, Na Liu, Yuji Toiyama, Masato Kusunoki, Takeshi Nagasaka, Toshiyoshi Fujiwara, Qing Wei, Huanlong Qin, Haifan Lin, Yanlei Ma, Ajay Goel
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Molecular Cancer
Subjects:
Colorectal cancer
piRNA
piR-1245
Prognosis
Biomarker
Noncoding RNA
Online Access:http://link.springer.com/article/10.1186/s12943-018-0767-3

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http://link.springer.com/article/10.1186/s12943-018-0767-3

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