Variation in the Phosphoinositide 3-Kinase Gamma Gene Affects Plasma HDL-Cholesterol without Modification of Metabolic or Inflammatory Markers.

Variation in the Phosphoinositide 3-Kinase Gamma Gene Affects Plasma HDL-Cholesterol without Modification of Metabolic or Inflammatory Markers.

<h4>Objective</h4>Phosphoinositide 3-kinase γ (PI3Kγ) is a G-protein-coupled receptor-activated lipid kinase mainly expressed in leukocytes and cells of the cardiovascular system. PI3Kγ plays an important signaling role in inflammatory processes. Since subclinical inflammation is a hallm...

Full description

Bibliographic Details
Main Authors: Martin Kächele, Anita M Hennige, Jürgen Machann, Anja Hieronimus, Apostolia Lamprinou, Fausto Machicao, Fritz Schick, Andreas Fritsche, Norbert Stefan, Bernd Nürnberg, Hans-Ulrich Häring, Harald Staiger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144494&type=printable

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144494&type=printable

Similar Items