Transforming Growth Factor-β Induces Interleukin-6 Secretion from Human Ligamentum Flavum–Derived Cells through Partial Activation of p38 and p44/42 Mitogen-Activated Protein Kinases

Transforming Growth Factor-β Induces Interleukin-6 Secretion from Human Ligamentum Flavum–Derived Cells through Partial Activation of p38 and p44/42 Mitogen-Activated Protein Kinases

Study Design This experimental study was performed using human ligamentum flavum–derived cells (HFCs). Purpose To investigate the intracellular signaling mechanism of interleukin-6 (IL-6) secretion in transforming growth factor-β (TGF-β)-stimulated HFCs. Overview of Literature Lumbar spinal stenosis...

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Bibliographic Details
Main Authors: Yuta Goto, Kenji Kato, Kiyoshi Yagi, Yohei Kawaguchi, Hiroki Yonezu, Tomoko Koshimae, Yuko Waguri-Nagaya, Hideki Murakami, Nobuyuki Suzuki
Format: Article
Language:English
Published: Korean Spine Society 2023-12-01
Series:Asian Spine Journal
Subjects:
map kinase
interleukin-6
transforming growth factor-β
spinal stenosis
ligamentum flavum
Online Access:http://asianspinejournal.org/upload/pdf/asj-2023-0025.pdf

Internet

http://asianspinejournal.org/upload/pdf/asj-2023-0025.pdf

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