In vitro antimicrobial combat, molecular modelling and structure activity relationship studies of novel class of aryl-ethyne tethered coumarin analogues and some 3-aryl coumarin derivatives
A series of novel class of aryl ethyne-tethered coumarin analogues (series 1) and some 3-aryl coumarin cognates (series 2) were synthesized, and their in vitro antimicrobial activities aided by molecular modelling and the structure activity relationship (SAR) has been studied. Compounds 1e, 1g, 1h,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-08-01
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| Series: | European Journal of Medicinal Chemistry Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772417422000206 |