In vitro antimicrobial combat, molecular modelling and structure activity relationship studies of novel class of aryl-ethyne tethered coumarin analogues and some 3-aryl coumarin derivatives
A series of novel class of aryl ethyne-tethered coumarin analogues (series 1) and some 3-aryl coumarin cognates (series 2) were synthesized, and their in vitro antimicrobial activities aided by molecular modelling and the structure activity relationship (SAR) has been studied. Compounds 1e, 1g, 1h,...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-08-01
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Series: | European Journal of Medicinal Chemistry Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772417422000206 |