Polymorphism analysis of pfmdr1 gene in Plasmodium falciparum isolates 11 years post-adoption of artemisinin-based combination therapy in Saudi Arabia

Polymorphism analysis of pfmdr1 gene in Plasmodium falciparum isolates 11 years post-adoption of artemisinin-based combination therapy in Saudi Arabia

Abstract A total of 227 Plasmodium falciparum isolates from Jazan region, southwestern Saudi Arabia were amplified for the P. falciparum multi-drug resistance 1 (pfmdr1) gene to detect point mutations 11 years after the introduction of artemisinin-based combination therapy (ACT) in Saudi Arabia. The...

Full description

Bibliographic Details
Main Authors: Hesham M. Al-Mekhlafi, Aymen M. Madkhali, Ahmed A. Abdulhaq, Wahib M. Atroosh, Ahmad Hassn Ghzwani, Khalid Ammash Zain, Khalid Y. Ghailan, Hassan A. Hamali, Abdullah A. Mobarki, Talal H. Alharazi, Zaki M. Eisa, Yee-Ling Lau
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-04450-x

Internet

https://doi.org/10.1038/s41598-021-04450-x

Similar Items