Food-Derived β-Carboline Alkaloids Ameliorate Lipid Droplet Accumulation in Human Hepatocytes

Food-Derived β-Carboline Alkaloids Ameliorate Lipid Droplet Accumulation in Human Hepatocytes

Lipid droplet accumulation (LDA) in hepatocytes is the initial stage of nonalcoholic fatty liver disease (NAFLD). In the search for natural compounds for the prevention of NAFLD, a series of β-carboline alkaloid derivatives, inspired by flazin and its derivative, newly identified in <i>Crassos...

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Bibliographic Details
Main Authors: Dya Fita Dibwe, Saki Oba, Nire Takeishi, Toshihiro Sakurai, Takayuki Tsukui, Hitoshi Chiba, Shu-Ping Hui
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceuticals
Subjects:
functional foods
<i>Crassostrea gigas</i>
β-carboline alkaloids
bioactive compounds
lipid droplet accumulation inhibition
lipidomics
Online Access:https://www.mdpi.com/1424-8247/15/5/578

Internet

https://www.mdpi.com/1424-8247/15/5/578

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