Live-Cell Imaging of the Contractile Velocity and Transient Intracellular Ca<sup>2+</sup> Fluctuations in Human Stem Cell-Derived Cardiomyocytes

Live-Cell Imaging of the Contractile Velocity and Transient Intracellular Ca<sup>2+</sup> Fluctuations in Human Stem Cell-Derived Cardiomyocytes

Live-cell imaging techniques are essential for acquiring vital physiological and pathophysiological knowledge to understand and treat heart disease. For live-cell imaging of transient alterations of [Ca<sup>2+</sup>]<sub>i</sub> in human cardiomyocytes, we engineered human-in...

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Bibliographic Details
Main Authors: Aviseka Acharya, Harshal Nemade, Krishna Rajendra Prasad, Khadija Khan, Jürgen Hescheler, Nick Blackburn, Ruth Hemmersbach, Symeon Papadopoulos, Agapios Sachinidis
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
hiPSCs
contractile velocity of cardiomyocytes
CRISPR-Cas9
genetically encoded Ca<sup>2+</sup>-indicator
drug screening
Online Access:https://www.mdpi.com/2073-4409/11/8/1280

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https://www.mdpi.com/2073-4409/11/8/1280

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