Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation

Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation

Tissue factor pathway inhibitor (TFPI) is an important regulator of coagulation and a link between inflammation and thrombosis. Here we investigated whether endothelial cell-driven oxidative post-translational modifications could have an impact on TFPI activity. We focused on S-sulfhydration, which...

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Bibliographic Details
Main Authors: Janina Wittig, Maria-Kyriaki Drekolia, Anastasia Kyselova, Fredy Delgado Lagos, Magdalena L. Bochenek, Jiong Hu, Katrin Schäfer, Ingrid Fleming, Sofia-Iris Bibli
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Redox Biology
Subjects:
TFPI
Endothelial CSE
S-sulfhydration
Coagulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723000952

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http://www.sciencedirect.com/science/article/pii/S2213231723000952

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