Folding Kinetics of Riboswitch Transcriptional Terminators and Sequesterers

Folding Kinetics of Riboswitch Transcriptional Terminators and Sequesterers

To function as gene regulatory elements in response to environmental signals, riboswitches must adopt specific secondary structures on appropriate time scales. We employ kinetic Monte Carlo simulation to model the time-dependent folding during transcription of thiamine pyrophosphate (TPP) riboswitch...

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Bibliographic Details
Main Authors: Ben Sauerwine, Michael Widom
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Entropy
Subjects:
nucleic acids
hairpin
folding
Monte Carlo
kinetic
simulation
Online Access:http://www.mdpi.com/1099-4300/15/8/3088

Internet

http://www.mdpi.com/1099-4300/15/8/3088

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