Breaking boundaries: role of the brain barriers in metastatic process

Abstract Brain metastases (BMs) are the most common intracranial tumors in adults and occur 3–10 times more frequently than primary brain tumors. Despite intensive multimodal therapies, including resection, radiotherapy, and chemotherapy, BMs are associated with poor prognosis and remain challenging...

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Bibliographic Details
Main Authors: Nasim Izadi, Peter Solár, Klaudia Hašanová, Alemeh Zamani, Maryam Shahidian Akbar, Klára Mrázová, Martin Bartošík, Tomáš Kazda, Roman Hrstka, Marek Joukal
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-025-00618-z