The role of m6A RNA methylation in human cancer

Abstract N6-methyladenosine (m6A) is identified as the most common, abundant and conserved internal transcriptional modification, especially within eukaryotic messenger RNAs (mRNAs). M6A modification is installed by the m6A methyltransferases (METTL3/14, WTAP, RBM15/15B and KIAA1429, termed as “writ...

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Bibliographic Details
Main Authors: Xiao-Yu Chen, Jing Zhang, Jin-Shui Zhu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Molecular Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12943-019-1033-z