Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2

Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2

Summary: Antibodies play a pivotal role in protecting from SARS-CoV-2 infection, but their efficacy is challenged by the continuous emergence of viral variants. In this study, we describe two broadly neutralizing antibodies cloned from the memory B cells of a single convalescent individual after inf...

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Bibliographic Details
Main Authors: Cyril Planchais, Ignacio Fernández, Benjamin Chalopin, Timothée Bruel, Pierre Rosenbaum, Maxime Beretta, Jordan D. Dimitrov, Laurine Conquet, Flora Donati, Matthieu Prot, Françoise Porrot, Delphine Planas, Isabelle Staropoli, Florence Guivel-Benhassine, Eduard Baquero, Sylvie van der Werf, Ahmed Haouz, Etienne Simon-Lorière, Xavier Montagutelli, Bernard Maillère, Félix A. Rey, Pablo Guardado-Calvo, Hervé Nozach, Olivier Schwartz, Hugo Mouquet
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:iScience
Subjects:
immunology
virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224015797

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224015797

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