High-fat diet-induced adipose tissue expansion occurs prior to insulin resistance in C57BL/6J mice

Background: To date, there is only scare evidence characterizing the temporal features and progression of metabolic dysfunction in high-fat diet (HFD)-fed obese mice. Hence, its specific pathogenesis remains unclear. Methods: Sixty 6-week-old male C57BL/6J mice were randomly divided into HFD and con...

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Bibliographic Details
Main Authors: Ming-Qian He, Jing-Ya Wang, Yue Wang, Jing Sui, Meng Zhang, Xi Ding, Yang Zhao, Zi-Yi Chen, Xiao-Xiao Ren, Bing-Yin Shi
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Chronic Diseases and Translational Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095882X20300621