Sphingosine-1-Phosphate Promotes the Persistence of Activated CD4 T Cells in Inflamed Sites

Sphingosine-1-Phosphate Promotes the Persistence of Activated CD4 T Cells in Inflamed Sites

Inflammation can be protective or pathogenic depending on context and timeframe. Acute inflammation, including the accumulation of CD4 T cells, accompanies protective immune responses to pathogens, but the presence of activated CD4 T cells at sites of inflammation is associated with chronic inflamma...

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Bibliographic Details
Main Authors: Shafqat Ahrar Jaigirdar, Robert A. Benson, Aziza Elmesmari, Mariola Stefania Kurowska-Stolarska, Iain B. McInnes, Paul Garside, Megan K. L. MacLeod
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
inflammation
CD4 T cell
sphingosine-1-phosphate
migration
intravital imaging
rheumatoid arthritis
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01627/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01627/full

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