Characterization of Naturally Acquired Immunity to a Panel of Antigens Expressed in Mature P. falciparum Gametocytes

IntroductionNaturally acquired immune responses against antigens expressed on the surface of mature gametocytes develop in individuals living in malaria-endemic areas. Evidence suggests that such anti-gametocyte immunity can block the development of the parasite in the mosquito, thus playing a role...

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Main Authors: Michelle K. Muthui, Eizo Takashima, Brian R. Omondi, Christine Kinya, William I. Muasya, Hikaru Nagaoka, Kennedy W. Mwai, Benedict Orindi, Juliana Wambua, Teun Bousema, Chris Drakeley, Andrew M. Blagborough, Kevin Marsh, Philip Bejon, Melissa C. Kapulu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.774537/full