Effect and mechanism of miRNA-144-5p-regulated autophagy in older adults with Sarcopenia

Abstract Background Advanced aging invariably triggers an overabundance of apoptosis, stemming from diminished autophagy or a disarray in cellular autophagic processes. This, in turn, leads to an accelerated breakdown of muscle proteins, which exacerbates the ongoing deterioration of skeletal muscle...

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Bibliographic Details
Main Authors: Mengdie Hu, Ying Zhang, Hong Ding, Rui Chao, Zhidong Cao
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-025-00499-8