Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis

Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis

Platelets have been recently described as an important component of the innate and adaptive immunity through their interaction with immune cells. However, information on the platelet–T cell interaction in immune-mediated diseases remains limited. Glycoprotein A repetitions predominant (GARP) express...

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Bibliographic Details
Main Authors: Niklas Zimmer, Franziska K. Krebs, Sophia Zimmer, Heidrun Mitzel-Rink, Elena J. Kumm, Kerstin Jurk, Stephan Grabbe, Carmen Loquai, Andrea Tuettenberg
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
GARP
platelets
Treg
melanoma
thrombocytosis
Online Access:https://www.mdpi.com/2072-6694/12/12/3653

Internet

https://www.mdpi.com/2072-6694/12/12/3653

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