Apical targeting of the formin Diaphanous in Drosophila tubular epithelia

Apical secretion from epithelial tubes of the Drosophila embryo is mediated by apical F-actin cables generated by the formin-family protein Diaphanous (Dia). Apical localization and activity of Dia are at the core of restricting F-actin formation to the correct membrane domain. Here we identify the...

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Bibliographic Details
Main Authors: Tal Rousso, Annette M Shewan, Keith E Mostov, Eyal D Schejter, Ben-Zion Shilo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/00666