Apical targeting of the formin Diaphanous in Drosophila tubular epithelia

Apical targeting of the formin Diaphanous in Drosophila tubular epithelia

Apical secretion from epithelial tubes of the Drosophila embryo is mediated by apical F-actin cables generated by the formin-family protein Diaphanous (Dia). Apical localization and activity of Dia are at the core of restricting F-actin formation to the correct membrane domain. Here we identify the...

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Bibliographic Details
Main Authors: Tal Rousso, Annette M Shewan, Keith E Mostov, Eyal D Schejter, Ben-Zion Shilo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-07-01
Series:eLife
Subjects:
Diaphanous
formin
tubular epithelia
apical localization
PI(4,5)P2
Rho1
Online Access:https://elifesciences.org/articles/00666

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