CRL Ubiquitin Ligases and DNA Damage Response
Cullin/RING ubiquitin ligases (CRL) comprise the largest subfamily of ubiquitin ligases and are involved in various biological processes. One of the main functions of CRLs is to regulate DNA damage response, a fundamental signaling cascade to maintain genome integrity. In this review, we will discus...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-04-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00029/full |