Integrative analysis of lung molecular signatures reveals key drivers of idiopathic pulmonary fibrosis

Integrative analysis of lung molecular signatures reveals key drivers of idiopathic pulmonary fibrosis

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease with a high clinical burden. The molecular signatures of IPF were analyzed to distinguish molecular subgroups and identify key driver genes and therapeutic targets. Methods Thirteen datasets of lung tissue transcriptomi...

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Bibliographic Details
Main Authors: Sung Kyoung Kim, Seung Min Jung, Kyung-Su Park, Ki-Jo Kim
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BMC Pulmonary Medicine
Subjects:
Idiopathic pulmonary fibrosis
Unsupervised clustering
Key driver genes
Online Access:https://doi.org/10.1186/s12890-021-01749-3

Internet

https://doi.org/10.1186/s12890-021-01749-3

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