Estrogen mediates inflammatory role of mast cells in endometriosis pathophysiology

Estrogen mediates inflammatory role of mast cells in endometriosis pathophysiology

Endometriosis is an estrogen dependent, chronic inflammatory disease characterized by the growth of endometrial lining outside of the uterus. Mast cells have emerged as key players in regulating not only allergic responses but also other mechanisms such as angiogenesis, fibrosis, and pain. The influ...

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Bibliographic Details
Main Authors: Alison McCallion, Yasmin Nasirzadeh, Harshavardhan Lingegowda, Jessica E. Miller, Kasra Khalaj, SooHyun Ahn, Stephany P. Monsanto, Mallikarjun Bidarimath, Danielle J. Sisnett, Andrew W. Craig, Steven L. Young, Bruce A. Lessey, Madhuri Koti, Chandrakant Tayade
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
endometriosis
immune microenvironment
mast cell recruitment and maturation
stem cell factor
immune crosstalk
estrogenic inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.961599/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.961599/full

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