Monoclonal antibodies effectively potentiate complement activation and phagocytosis of Staphylococcus epidermidis in neonatal human plasma

Monoclonal antibodies effectively potentiate complement activation and phagocytosis of Staphylococcus epidermidis in neonatal human plasma

Central line associated bloodstream infections (CLABSI) with Staphylococcus epidermidis are a major cause of morbidity in neonates, who have an increased risk of infection because of their immature immune system. As especially preterm neonates suffer from antibody deficiency, clinical studies into p...

Full description

Bibliographic Details
Main Authors: Lisanne de Vor, Coco R. Beudeker, Anne Flier, Lisette M. Scheepmaker, Piet C. Aerts, Daniel C. Vijlbrief, Mireille N. Bekker, Frank J. Beurskens, Kok P. M. van Kessel, Carla J. C. de Haas, Suzan H. M. Rooijakkers, Michiel van der Flier
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
complement system
CLABSI
Staphylococcus epidermidis
monoclonal antibodies
phagocytosis
neonates
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.933251/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.933251/full

Similar Items