Taxol acts differently on different tubulin isotypes
Abstract Taxol is a small molecule effector that allosterically locks tubulin into the microtubule lattice. We show here that taxol has different effects on different single-isotype microtubule lattices. Using in vitro reconstitution, we demonstrate that single-isotype α1β4 GDP-tubulin lattices are...
| Autors principals: | , |
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| Format: | Article |
| Idioma: | English |
| Publicat: |
Nature Portfolio
2023-09-01
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| Col·lecció: | Communications Biology |
| Accés en línia: | https://doi.org/10.1038/s42003-023-05306-y |