Mapping of neuroinflammation-induced hypoxia in the spinal cord using optoacoustic imaging

Mapping of neuroinflammation-induced hypoxia in the spinal cord using optoacoustic imaging

Abstract Recent studies suggest that metabolic changes and oxygen deficiency in the central nervous system play an important role in the pathophysiology of multiple sclerosis (MS). In our present study, we investigated the changes in oxygenation and analyzed the vascular perfusion of the spinal cord...

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Bibliographic Details
Main Authors: Marta Ramos-Vega, Pontus Kjellman, Mihail Ivilinov Todorov, Tekla Maria Kylkilahti, B. Thomas Bäckström, Ali Ertürk, Chris Denis Madsen, Iben Lundgaard
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Acta Neuropathologica Communications
Subjects:
Neuroinflammation
Hypoxia
Optoacoustic imaging
Light sheet fluorescence microscopy
EAE
Multiple sclerosis
Online Access:https://doi.org/10.1186/s40478-022-01337-4

Internet

https://doi.org/10.1186/s40478-022-01337-4

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