Mapping metabolite change in the mouse brain after esketamine injection by ambient mass spectrometry imaging and metabolomics

Ketamine is a new, fast, and effective antidepression treatment method; however, the possible dissociation effects, sensory changes, abuse risk, and the inability to accurately identify whether patients have a significant response to ketamine limit its clinical use. Further exploration of the antide...

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Bibliographic Details
Main Authors: Guan-Xi Liu, Ze-Lin Li, Su-Yan Lin, Qian Wang, Zheng-Yi Luo, Kai Wu, Yan-Lin Zhou, Yu-Ping Ning
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1109344/full