Deubiquitinase OTUD6A Regulates Innate Immune Response via Targeting UBC13

Deubiquitinase OTUD6A Regulates Innate Immune Response via Targeting UBC13

OTUD6A is a deubiquitinase that plays crucial roles in various human diseases. However, the precise regulatory mechanism of OTUD6A remains unclear. In this study, we found that OTUD6A significantly inhibited the production of type I interferon. Consistently, peritoneal macrophages and bone marrow-de...

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Bibliographic Details
Main Authors: Zhiwei Li, Guanwen Li, Yunfei Li, Yujie Luo, Yuhan Jiang, Ziyu Zhang, Ziyi Zhou, Shengde Liu, Chen Wu, Fuping You
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Viruses
Subjects:
OTUD6A
IFNβ
UBC13
NF-κB
innate immunity
Online Access:https://www.mdpi.com/1999-4915/15/8/1761

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https://www.mdpi.com/1999-4915/15/8/1761

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