Fibulin7 Mediated Pathological Cardiac Remodeling through EGFR Binding and EGFR‐Dependent FAK/AKT Signaling Activation

Fibulin7 Mediated Pathological Cardiac Remodeling through EGFR Binding and EGFR‐Dependent FAK/AKT Signaling Activation

Abstract Adverse remodeling after myocardial infarction (MI) result in heart failure and sudden cardiac death. Fibulin7 (FBLN7) is an adhesion protein excreted into the extracellular matrix that functions in multiple biological processes. However, whether and how FBLN7 affects post‐MI cardiac remode...

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Bibliographic Details
Main Authors: Xuehui Zheng, Lingxin Liu, Jing Liu, Chen Zhang, Jie Zhang, Yan Qi, Lin Xie, Chunmei Zhang, Guoqing Yao, Peili Bu
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Advanced Science
Subjects:
EGFR
fibrosis
fibulin 7
myocardial infarction
myofibroblasts
Online Access:https://doi.org/10.1002/advs.202207631

Internet

https://doi.org/10.1002/advs.202207631

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