CD4+ T-cell independent secondary immune responses to Pneumocystis pneumonia

CD4+ T-cell independent secondary immune responses to Pneumocystis pneumonia

Pneumocystis pneumonia is a major cause of morbidity and mortality among immunocompromised patients, especially in the context of HIV/AIDS. In the murine model of Pneumocystis pneumonia, CD4+ T-cells are required for clearance of a primary infection of Pneumocystis but not the memory recall response...

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Bibliographic Details
Main Authors: Nicholas M de la Rua, Derrick Richard Samuelson, Tysheena P Charles, David Allen Welsh, Judd E. Shellito
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Immunology
Subjects:
Macrophages
Pneumocystis
Pneumonia
immune memory
CD8+ T-cells
BMPCs
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00178/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00178/full

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