Synthesis of New Pyrazole and Pyrimidine Steroidal Derivatives

Synthesis of New Pyrazole and Pyrimidine Steroidal Derivatives

The synthesis of steroidal heterocycles containing the pyrazole and pyrimidine ring fused to the 16,17-position of the steroid nucleus is reported. Androstenolone acetate (1) reacted with carbon disulfide, iodomethane and sodium hydride to furnish 3β-acetoxy-16-[bis(methylthio)methylene]-5-andros...

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Bibliographic Details
Main Authors: Francisco Coll, Reinaldo Molina, Alina Montero, Isabel Jomarrón, Klaus Peseke, Daniel G. Rivera
Format: Article
Language:English
Published: MDPI AG 2003-05-01
Series:Molecules
Subjects:
Androstenolone
steroidal heterocycles
push-pull alkenes
pyrazoles
pyrimidines
Online Access:http://www.mdpi.com/1420-3049/8/5/444/

Internet

http://www.mdpi.com/1420-3049/8/5/444/

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