Transcriptional differences between rhesus embryonic stem cells generated from in vitro and in vivo derived embryos.

Numerous studies have focused on the transcriptional signatures that underlie the maintenance of embryonic stem cell (ESC) pluripotency. However, it remains unclear whether ESC retain transcriptional aberrations seen in in vitro cultured embryos. Here we report the first global transcriptional profi...

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Bibliographic Details
Main Authors: Alexandra J Harvey, Shihong Mao, Claudia Lalancette, Stephen A Krawetz, Carol A Brenner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3445581?pdf=render