Selective activation of PPARα maintains thermogenic capacity of beige adipocytes

Selective activation of PPARα maintains thermogenic capacity of beige adipocytes

Summary: Beige adipocytes are inducible thermogenic adipocytes used for anti-obesity treatment. Beige adipocytes rapidly lose their thermogenic capacity once external cues are removed. However, long-term administration of stimulants, such as PPARγ and β-adrenergic receptor agonists, is unsuitable du...

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Bibliographic Details
Main Authors: Gentaro Egusa, Haruya Ohno, Gaku Nagano, Junji Sagawa, Hiroko Shinjo, Yutaro Yamamoto, Natsumi Himeno, Yoshimi Morita, Akinori Kanai, Ryuta Baba, Kazuhiro Kobuke, Kenji Oki, Masayasu Yoneda, Noboru Hattori
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Molecular biology
Cell biology
Animal Physiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012208

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223012208

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