The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.

The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.

SLC18B1 is a sister gene to the vesicular monoamine and acetylcholine transporters, and the only known polyamine transporter, with unknown physiological role. We reveal that Slc18b1 knock out mice has significantly reduced polyamine content in the brain providing the first evidence that Slc18b1 is f...

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Bibliographic Details
Main Authors: Robert Fredriksson, Smitha Sreedharan, Karin Nordenankar, Johan Alsiö, Frida A Lindberg, Ashley Hutchinson, Anders Eriksson, Sahar Roshanbin, Diana M Ciuculete, Anica Klockars, Aniruddha Todkar, Maria G Hägglund, Sofie V Hellsten, Viktoria Hindlycke, Åke Västermark, Ganna Shevchenko, Gaia Olivo, Cheng K, Klas Kullander, Ali Moazzami, Jonas Bergquist, Pawel K Olszewski, Helgi B Schiöth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008455

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https://doi.org/10.1371/journal.pgen.1008455

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