Design, Synthesis, and Anticancer Activity of Novel Enmein-Type Diterpenoid Derivatives Targeting the PI3K/Akt/mTOR Signaling Pathway

The enmein-type diterpenoids are a class of anticancer <i>ent</i>-Kaurane diterpnoids that have received much attention in recent years. Herein, a novel 1,14-epoxy enmein-type diterpenoid <b>4</b>, was reported in this project for the first time. A series of novel enmein-type...

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Bibliographic Details
Main Authors: Jiafeng Wang, Lu Wang, Yingbo Zhang, Siwen Pan, Yu Lin, Jiale Wu, Ming Bu
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/17/4066