Is serum‐derived exosomal hTERT transcript a marker of oncogenic activity in primary brain tumors? An exploratory study

Is serum‐derived exosomal hTERT transcript a marker of oncogenic activity in primary brain tumors? An exploratory study

Abstract Background In order to proliferate indefinitely, all tumors require a telomere maintenance mechanism. The expression of human telomerase reverse transcriptase (hTERT) enables telomere maintenance and provides cancer cells with limitless replicative potential. As such, it may serve as an att...

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Bibliographic Details
Main Authors: Orit Uziel, Andrew A. Kanner, Einat Beery, Sapir Lev, Meir Lahav, Suzana Horn‐Fichman, Sagi Har Nof, Yuseph Laviv, S. Yust‐Katz, Alexandra Amiel, Ramez Abu Shkara, Mustafa Siddeeq, Adva Levy‐Barda, Pia Raanani, Yaron Sela, Zvi Cohen, Tali Siegal
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Cancer Medicine
Subjects:
atypical meningioma
exosomes
glioblastoma
liquid biopsy
meningioma
telomerase
Online Access:https://doi.org/10.1002/cam4.6784

Internet

https://doi.org/10.1002/cam4.6784

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