Bile acid interactions with neurotransmitter transporters

Bile acid interactions with neurotransmitter transporters

Synthesized in the liver from cholesterol, the bile acids (BAs) primary role is emulsifying fats to facilitate their absorption. BAs can cross the blood-brain barrier (BBB) and be synthesized in the brain. Recent evidence suggests a role for BAs in the gut-brain signaling by modulating the activity...

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Bibliographic Details
Main Authors: Tiziana Romanazzi, Daniele Zanella, Manan Bhatt, Angela Di Iacovo, Aurelio Galli, Elena Bossi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
SLC6
bile acids
dopamine transporter
obeticholic acid (OCA)
two-electrode voltage clamp
GABA transporter 1
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1161930/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1161930/full

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