Copper-promoted C5-selective bromination of 8-aminoquinoline amides with alkyl bromides

Copper-promoted C5-selective bromination of 8-aminoquinoline amides with alkyl bromides

An efficient and practical method for the synthesis of C5-brominated 8-aminoquinoline amides via a copper-promoted selective bromination of 8-aminoquinoline amides with alkyl bromides was developed. The reaction proceeds smoothly in dimethyl sulfoxide (DMSO) under air, employing activated and unacti...

Full description

Bibliographic Details
Main Authors: Changdong Shao, Chen Ma, Li Li, Jingyi Liu, Yanan Shen, Chen Chen, Qionglin Yang, Tianyi Xu, Zhengsong Hu, Yuhe Kan, Tingting Zhang
Format: Article
Language:English
Published: Beilstein-Institut 2024-01-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
aminoquinolines
c–h bromination
copper catalysis
regioselectivity
Online Access:https://doi.org/10.3762/bjoc.20.14

Internet

https://doi.org/10.3762/bjoc.20.14

Similar Items