FK506 Binding Protein Mediates Glioma Cell Growth and Sensitivity to Rapamycin Treatment by Regulating NF-κB Signaling Pathway

FK506 Binding Protein Mediates Glioma Cell Growth and Sensitivity to Rapamycin Treatment by Regulating NF-κB Signaling Pathway

FK506 binding protein 5 (FKBP5) belongs to a family of immunophilins named for their ability to bind immunosuppressive drugs, also known as peptidyl-prolyl cis-trans isomerases, and also with chaperones to help protein folding. Using glioma cDNA microarray analysis, we found that FKBP5 was overexpre...

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Bibliographic Details
Main Authors: Wei Jiang, Simona Cazacu, Cunli Xiang, Jean C Zenklusen, Howard A Fine, Michael Berens, Brock Armstrong, Chaya Brodie, Tom Mikkelsen
Format: Article
Language:English
Published: Elsevier 2008-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608801200

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http://www.sciencedirect.com/science/article/pii/S1476558608801200

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