The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy

The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy

Primary clear cell renal cell carcinoma (ccRCC) has been previously characterized, but the genomic landscape of metastatic ccRCC is largely unexplored. Here, we performed whole exome sequencing (WES) in 68 samples from 44 patients with ccRCC, including 52 samples from a metastatic site. SETD2, PBRM1...

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Bibliographic Details
Main Authors: Johannes C. van derMijn, Kenneth W. Eng, Pooja Chandra, Evan Fernandez, Sinan Ramazanoglu, Alexandros Sigaras, Clara Oromendia, Lorraine J. Gudas, Scott T. Tagawa, David M. Nanus, Bishoy F. Faltas, Himisha Beltran, Cora N. Sternberg, Olivier Elemento, Andrea Sboner, Juan Miguel Mosquera, Ana M. Molina
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Molecular Oncology
Subjects:
cancer
genomics
immunotherapy
kidney
metastasis
VEGF
Online Access:https://doi.org/10.1002/1878-0261.13204

Internet

https://doi.org/10.1002/1878-0261.13204

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