Better Response to Influenza Virus Vaccination in Physically Trained Older Adults Is Associated With Reductions of Cytomegalovirus-Specific Immunoglobulins as Well as Improvements in the Inflammatory and CD8+ T-Cell Profiles

Better Response to Influenza Virus Vaccination in Physically Trained Older Adults Is Associated With Reductions of Cytomegalovirus-Specific Immunoglobulins as Well as Improvements in the Inflammatory and CD8+ T-Cell Profiles

Chronic cytomegalovirus (CMV) infection is a trigger factor for the development of immunosenescence and negatively impacts the immune response to influenza virus vaccination (IVV) in older adults. However, the role of physical exercise training in this context is unknown. Thus, the aim of this study...

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Bibliographic Details
Main Authors: Eduardo S. Felismino, Juliana M. B. Santos, Marcelo Rossi, Carlos A. F. Santos, Edison L. Durigon, Danielle B. L. Oliveira, Luciano M. Thomazelli, Fernanda R. Monteiro, Adriane Sperandio, Juliana S. Apostólico, Carolina N. França, Jonatas B. Amaral, Gislene R. Amirato, Rodolfo P. Vieira, Mauro Vaisberg, André L. L. Bachi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
cytomegalovirus
influenza virus vaccine
cytokines
immunoglobulin
exercise training
elderly
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.713763/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.713763/full

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