Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection

Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection

Atomically precise gold nanoclusters hold promise as non-linear optical probes for biological imaging. Here functionalized luminescent gold nanoclusters bind free carbonyls via oxime bond formation, allowing detection of carbonylated proteins via gel electrophoresis and fluorescence imaging.

Bibliographic Details
Main Authors: Guillaume F. Combes, Hussein Fakhouri, Christophe Moulin, Marion Girod, Franck Bertorelle, Srestha Basu, Romain Ladouce, Martina Perić Bakulić, Željka Sanader Maršić, Isabelle Russier-Antoine, Pierre-François Brevet, Philippe Dugourd, Anita Krisko, Katarina Trajković, Miroslav Radman, Vlasta Bonačić-Koutecký, Rodolphe Antoine
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-021-00497-z

Internet

https://doi.org/10.1038/s42004-021-00497-z

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