Synthesis and Characterization of Andrographolide Derivatives as Regulators of βAPP Processing in Human Cells

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder, one of the main characteristics of which is the abnormal accumulation of amyloid peptide (Aβ) in the brain. Whereas β-secretase supports Aβ formation along the amyloidogenic processing of the β-amyloid precursor protein (βAPP), α-...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Arpita Dey, Ran Chen, Feng Li, Subhamita Maitra, Jean-Francois Hernandez, Guo-Chun Zhou, Bruno Vincent
التنسيق: مقال
اللغة:English
منشور في: MDPI AG 2021-12-01
سلاسل:Molecules
الموضوعات:
الوصول للمادة أونلاين:https://www.mdpi.com/1420-3049/26/24/7660