Synthesis and Characterization of Andrographolide Derivatives as Regulators of βAPP Processing in Human Cells

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder, one of the main characteristics of which is the abnormal accumulation of amyloid peptide (Aβ) in the brain. Whereas β-secretase supports Aβ formation along the amyloidogenic processing of the β-amyloid precursor protein (βAPP), α-...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Arpita Dey, Ran Chen, Feng Li, Subhamita Maitra, Jean-Francois Hernandez, Guo-Chun Zhou, Bruno Vincent
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: MDPI AG 2021-12-01
Σειρά:Molecules
Θέματα:
Διαθέσιμο Online:https://www.mdpi.com/1420-3049/26/24/7660